4gp0
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gp0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gp0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gp0 RCSB], [http://www.ebi.ac.uk/pdbsum/4gp0 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gp0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gp0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gp0 RCSB], [http://www.ebi.ac.uk/pdbsum/4gp0 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/FSCN1_HUMAN FSCN1_HUMAN]] Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration.<ref>PMID:9362073</ref> <ref>PMID:9571235</ref> <ref>PMID:20137952</ref> <ref>PMID:20393565</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 19:59, 25 December 2014
The crystal structure of human fascin 1 R149A K150A R151A mutant
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Categories: Homo sapiens | Chen, L | Chen, S | Diaz-Avalos, R | Huang, F K | Huang, J | Huang, X Y | Jakoncic, J | Leo-Macias, A | Yang, S Y | Zhang, J J | Actin | Actin bundling protein | Actin-binding | Beta-trefoil | Cancer | Cell migration | Metastasis | Phosphoprotein | Protein binding
