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4gjz
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gjz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gjz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gjz RCSB], [http://www.ebi.ac.uk/pdbsum/4gjz PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gjz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gjz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gjz RCSB], [http://www.ebi.ac.uk/pdbsum/4gjz PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/KDM8_HUMAN KDM8_HUMAN]] Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 18:42, 25 December 2014
JMJD5 in complex with 2-oxoglutarate
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