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4hru
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hru FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hru OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hru RCSB], [http://www.ebi.ac.uk/pdbsum/4hru PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hru FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hru OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hru RCSB], [http://www.ebi.ac.uk/pdbsum/4hru PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 14:21, 25 December 2014
Molecular tweezers modulate 14-3-3 protein-protein interactions
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