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Sigma factor

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Line 44: Line 44:
**[[2mao]] – EcSF region 2 - NMR<br />
**[[2mao]] – EcSF region 2 - NMR<br />
**[[1tty]] – TmSF-70 region 4 – ''Thermotoga maritima''<br />
**[[1tty]] – TmSF-70 region 4 – ''Thermotoga maritima''<br />
-
**[[1tty]] – TmSF-70 region 1.1 (mutant) - NMR<br />
+
**[[2k6x]] – TmSF-70 region 1.1 (mutant) - NMR<br />
**[[2ahq]] – AaSF-54 C terminal – ''Aquifex aeolicus'' - NMR<br />
**[[2ahq]] – AaSF-54 C terminal – ''Aquifex aeolicus'' - NMR<br />
**[[2k9l]], [[2k9m]] – AaSF-54 core domain - NMR<br />
**[[2k9l]], [[2k9m]] – AaSF-54 core domain - NMR<br />
**[[3mzy]] – SF-H – ''Fusobacterium nucleatum''<br />
**[[3mzy]] – SF-H – ''Fusobacterium nucleatum''<br />
 +
**[[1h3l]] – SF N terminal – ''Streptomyces coelicolor''<br />
*Sigma factor complex with DNA
*Sigma factor complex with DNA
Line 55: Line 56:
**[[2h27]] – EcSF-E region 4 + DNA<br />
**[[2h27]] – EcSF-E region 4 + DNA<br />
**[[2map]] – EcSF region 2 + DNA - NMR<br />
**[[2map]] – EcSF region 2 + DNA - NMR<br />
 +
**[[1ku7]] – EcSF region 4 (mutant) + DNA <br />
**[[2o8k]], [[2o9l]] – AaSF-54 C terminal + DNA - NMR<br />
**[[2o8k]], [[2o9l]] – AaSF-54 C terminal + DNA - NMR<br />
Line 67: Line 69:
**[[3hug]] – MtSF + membrane protein – ''Mycobacterium tuberculosis''<br />
**[[3hug]] – MtSF + membrane protein – ''Mycobacterium tuberculosis''<br />
**[[4nqw]] – MtSF-K region 4 + anti-σ factor<br />
**[[4nqw]] – MtSF-K region 4 + anti-σ factor<br />
-
**[[3wod]] – TtSF + RNAP subunits α,β,β’,ω - ''Thermus thermophilus'' <br />
+
**[[4x8k]] – MtSF-A region 2 + RBPA<br />
-
**[[4mq9]] – TtSF-70 + RNAP subunits α,β,β’,ω + antibiotic <br />
+
**[[3wod]], [[2a6e]], [[2cw0]] – TtSF + RNAP subunits α,β,β’,ω - ''Thermus thermophilus'' <br />
 +
**[[4mq9]], [[2a68]], [[2a69]], [[2a6h]], [[3dxj]], [[3eql]] – TtSF-70 + RNAP subunits α,β,β’,ω + antibiotic <br />
 +
**[[2be5]] – TtSF + RNAP subunits α,β,β’,ω + inhibitor<br />
**[[1l9u]] – TaSF region 1.1-4 + RNAP subunits α,β,β’,ω<br />
**[[1l9u]] – TaSF region 1.1-4 + RNAP subunits α,β,β’,ω<br />
-
**[[4mex]] – EcSF-70 + RNAP subunits α,β,β’,ω + antibiotic <br />
+
**[[4yg2]] – EcSF-70 + RNAP subunits α,β,β’,ω <br />
 +
**[[4mex]], [[4kmu]], [[4kn4]], [[4kn7]] – EcSF-70 + RNAP subunits α,β,β’,ω + antibiotic <br />
**[[4mey]], [[4ljz]], [[4lk1]] – EcSF-70 + RNAP subunits α,β,β’,ω <br />
**[[4mey]], [[4ljz]], [[4lk1]] – EcSF-70 + RNAP subunits α,β,β’,ω <br />
-
**[[4lk0]], [[4llg]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + RNAP inhibitor<br />
+
**[[4lk0]], [[4llg]], [[4yfk]], [[4yfn]], [[4yfx]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + RNAP inhibitor<br />
**[[4cxf]] – SF CNRH + CNRY – ''Cupriavidus metallidurans''<br />
**[[4cxf]] – SF CNRH + CNRY – ''Cupriavidus metallidurans''<br />
**[[4g6d]], [[4g8x]], [[4g94]] – SF-70 region 4 + Orf067 – ''Staphylococcus aureus''<br />
**[[4g6d]], [[4g8x]], [[4g94]] – SF-70 region 4 + Orf067 – ''Staphylococcus aureus''<br />
Line 80: Line 85:
**[[1rio]] - TaSF region 4 + repression protein CI + DNA<br />
**[[1rio]] - TaSF region 4 + repression protein CI + DNA<br />
**[[4oin]], [[4oip]], [[4oiq]], [[4oir]] – TtSF-A + RNAP subunits α,β,β’,ω + antibiotic + DNA<br />
**[[4oin]], [[4oip]], [[4oiq]], [[4oir]] – TtSF-A + RNAP subunits α,β,β’,ω + antibiotic + DNA<br />
-
**[[4oio]] – TtSF-A + RNAP subunits α,β,β’,ω + DNA<br />
+
**[[4oio]], [[4g7h]], [[4g7o]], [[4g7z]], [[4q4z]], [[4q5s]] – TtSF-A + RNAP subunits α,β,β’,ω + DNA<br />
 +
**[[1smy]] – TtSF + RNAP subunits α,β,β’,ω + G4P<br />
**[[3n97]] – TaSF region 4 + RNAP subunits α + DNA<br />
**[[3n97]] – TaSF region 4 + RNAP subunits α + DNA<br />
-
**[[1l9u]] – TaSF + RNAP subunits α,β,β’,ω + DNA – Cryo EM <br />
+
**[[1l9u]], [[1l9z]] – TaSF + RNAP subunits α,β,β’,ω + DNA – Cryo EM <br />
**[[3iyd]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + catabolite gene activator + DNA<br />
**[[3iyd]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + catabolite gene activator + DNA<br />
 +
**[[4jk1]], [[4jk2]], [[4jkr]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + G4P<br />
 +
**[[4yln]], [[4ylo]], [[4ylp]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + DNA<br />
 +
}}
}}
== References ==
== References ==

Revision as of 09:14, 16 June 2015

Structure of sigma factor of E.Coli RNAP in complex with Promoter DNA (PDB code 4lup).

Drag the structure with the mouse to rotate

3D structures of sigma factor

Updated on 16-June-2015

References

1. Felklistov, Andrey, Brian D. Sharon, Seth A. Darst, and Carol A. Gross. "Bacterial Sigma Factors: A Historical, Structural, and Genomic Perspective." The Annual Review of Microbiology 68 (2014): 357-76.

2. Voet, Donald, Judith G. Voet, and Charlotte W. Pratt. Fundamentals of Biochemistry: Life at the Molecular Level. 3rd ed. Hoboken, NJ: Wiley, 2008.

3. Mooney, R. A., S. A. Darst, and R. Landick. "Sigma and RNA Polymerase: An On-again, Off-again Relationship?" Molecular Cell 20.3 (2005): 335-45.


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