4wsf
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wsf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wsf RCSB], [http://www.ebi.ac.uk/pdbsum/4wsf PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wsf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wsf RCSB], [http://www.ebi.ac.uk/pdbsum/4wsf PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PP4R3_DROME PP4R3_DROME]] Regulatory subunit of serine/threonine-protein phosphatase 4. The probable PP4 complex Pp4-19C-PPP4R2r-flfl (PPP4C-PPP4R2-PPP4R3) is required to prevent caspase induced cell death (in vitro). May be involved in DNA damage repair. Key mediator specific for the localization of mira and associated cell fate determinants during both interphase and mitosis. Nuclear Flfl is required to exclude mira/pros from the nucleus when inefficiently bound to the cytoskeleton/cortex, whereas cytosolic or membrane-associated flfl is required for the cortical association and asymmetric localization of mira/pros/brat/stau at metaphase and anaphase.<ref>PMID:16085932</ref> <ref>PMID:18487071</ref> <ref>PMID:19204120</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 21:14, 25 December 2014
Falafel EVH1 domain bound to CENP-C FIM
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