T-cell receptor
From Proteopedia
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{{STRUCTURE_2xna| PDB=2xna | SIZE=400| SCENE= |right|CAPTION= T-cell receptor α chain (grey), β chain (green) complex with enterotoxin (pink), glycerol and Na+ ion (purple) [[2xna]].}} | {{STRUCTURE_2xna| PDB=2xna | SIZE=400| SCENE= |right|CAPTION= T-cell receptor α chain (grey), β chain (green) complex with enterotoxin (pink), glycerol and Na+ ion (purple) [[2xna]].}} | ||
| - | '''T-cell receptors''' (TCR) reside on the surface of T lymphocytes. TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. The binding of TCR to the antigen-MHC activates the T lymphocytes. TCR is a heterodimer α+β and ca. 5% the T cells have a γ+δ heterodimer. For more details see [[SP3.4-TCR-HLA-DQ8-∝-1-gliadin_complex]]. | + | '''T-cell receptors''' (TCR) reside on the surface of T lymphocytes. TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. The binding of TCR to the antigen-MHC activates the T lymphocytes. TCR is a heterodimer of α+β subunits and ca. 5% the T cells have a γ+δ subumits TCR heterodimer. For more details see [[SP3.4-TCR-HLA-DQ8-∝-1-gliadin_complex]]. |
== 3D structures of T-cell receptor== | == 3D structures of T-cell receptor== | ||
Revision as of 10:33, 11 December 2014
T-cell receptors (TCR) reside on the surface of T lymphocytes. TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. The binding of TCR to the antigen-MHC activates the T lymphocytes. TCR is a heterodimer of α+β subunits and ca. 5% the T cells have a γ+δ subumits TCR heterodimer. For more details see SP3.4-TCR-HLA-DQ8-∝-1-gliadin_complex.
3D structures of T-cell receptor
Updated on 11-December-2014
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Michal Harel, Alexander Berchansky, Joel L. Sussman, Jaime Prilusky
