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4uy1

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uy1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uy1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uy1 RCSB], [http://www.ebi.ac.uk/pdbsum/4uy1 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uy1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uy1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uy1 RCSB], [http://www.ebi.ac.uk/pdbsum/4uy1 PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PA2GX_HUMAN PA2GX_HUMAN]] PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Has a powerful potency for releasing arachidonic acid from cell membrane phospholipids. Prefers phosphatidylethanolamine and phosphatidylcholine liposomes to those of phosphatidylserine.
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

Revision as of 02:18, 25 December 2014

Novel pyrazole series of group X Secretory Phospholipase A2 (sPLA2-X) inhibitors

4uy1, resolution 2.20Å

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