This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Villin
From Proteopedia
(Difference between revisions)
| Line 24: | Line 24: | ||
**[[1yu5]], [[1qqv]] - cVIL headpiece<br /> | **[[1yu5]], [[1qqv]] - cVIL headpiece<br /> | ||
**[[3myc]], [[3mye]], [[3nkj]], [[3mya]], [[3tjw]], [[3trv]], [[3trw]], [[3try]] - cVIL headpiece (mutant)<br /> | **[[3myc]], [[3mye]], [[3nkj]], [[3mya]], [[3tjw]], [[3trv]], [[3trw]], [[3try]] - cVIL headpiece (mutant)<br /> | ||
| - | **[[1vii]], [[2vik]], [[2vil]] - cVIL headpiece - NMR<br /> | + | **[[1vii]], [[2vik]], [[2vil]], [[4cz3]], [[4cz4]] - cVIL headpiece - NMR<br /> |
**[[2ppz]], [[2jm0]] - VIL headpiece (mutant) – synthetic – NMR<br /> | **[[2ppz]], [[2jm0]] - VIL headpiece (mutant) – synthetic – NMR<br /> | ||
**[[2f4k]], [[1wy3]], [[1wy4]], [[1yrf]], [[1yri]] - VIL fragment (mutant) – synthetic<br /> | **[[2f4k]], [[1wy3]], [[1wy4]], [[1yrf]], [[1yri]] - VIL fragment (mutant) – synthetic<br /> | ||
Revision as of 08:12, 25 June 2015
- Villin (VIL) is an actin-binding protein. It contains gelsolin-like domains in its N-terminal and a helical headpiece which binds actin[1].
- Supervillin (SVIL) contains numerous gelsolin-like domains in its C-terminal and interacts with actin.
- Advillin (AVIL) is another actin-binding protein in the gelsolin superfamily which is expressed in the peripheral sensory neurons.
- Cytovillin (CVIL) or ezrin or villin-2 serves as intermediate between plasma membrane and actin cytoskeleton.
3D Structures of Villin
Updated on 25-June-2015
References
- ↑ Friederich E, Vancompernolle K, Louvard D, Vandekerckhove J. Villin function in the organization of the actin cytoskeleton. Correlation of in vivo effects to its biochemical activities in vitro. J Biol Chem. 1999 Sep 17;274(38):26751-60. PMID:10480879
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, David Canner, Jaime Prilusky, Joel L. Sussman
