4x9k

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m (Protected "4x9k" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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==Beta-ketoacyl-acyl carrier protein synthase III-2 (FabH2)(C113A) from Vibrio cholerae==
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<StructureSection load='4x9k' size='340' side='right' caption='[[4x9k]], [[Resolution|resolution]] 1.61&Aring;' scene=''>
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The entry 4x9k is ON HOLD
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4x9k]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X9K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X9K FirstGlance]. <br>
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Authors: Hou, J
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wzu|4wzu]], [[4x9o|4x9o]]</td></tr>
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Description: Beta-ketoacyl-acyl carrier protein synthase III-2 (FabH2)(C113A) from Vibrio cholerae
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-ketoacyl-[acyl-carrier-protein]_synthase_III Beta-ketoacyl-[acyl-carrier-protein] synthase III], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.180 2.3.1.180] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x9k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x9k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4x9k RCSB], [http://www.ebi.ac.uk/pdbsum/4x9k PDBsum]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/FABH2_VIBCH FABH2_VIBCH]] Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.[HAMAP-Rule:MF_01815]
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__TOC__
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</StructureSection>
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[[Category: Structural genomic]]
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[[Category: Hou, J]]
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[[Category: Csgid]]
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[[Category: Fabh]]
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[[Category: Transferase]]

Revision as of 11:17, 24 December 2014

Beta-ketoacyl-acyl carrier protein synthase III-2 (FabH2)(C113A) from Vibrio cholerae

4x9k, resolution 1.61Å

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