2mmu

Structural highlights

Function

[CRGA_MYCTU] Involved in cell division. Plays an important role in septal peptidoglycan synthesis and cell shape morphogenesis. May facilitate the recruitment of the peptidoglycan synthesis machinery to poles and septal zones and coordinate peptidoglycan synthesis at these sites.[HAMAP-Rule:MF_00631]^{[1] [2]}

References

1. ↑ Plocinski P, Ziolkiewicz M, Kiran M, Vadrevu SI, Nguyen HB, Hugonnet J, Veckerle C, Arthur M, Dziadek J, Cross TA, Madiraju M, Rajagopalan M. Characterization of CrgA, a new partner of the Mycobacterium tuberculosis peptidoglycan polymerization complexes. J Bacteriol. 2011 Jul;193(13):3246-56. doi: 10.1128/JB.00188-11. Epub 2011 Apr, 29. PMID:21531798 doi:http://dx.doi.org/10.1128/JB.00188-11
2. ↑ Plocinski P, Arora N, Sarva K, Blaszczyk E, Qin H, Das N, Plocinska R, Ziolkiewicz M, Dziadek J, Kiran M, Gorla P, Cross TA, Madiraju M, Rajagopalan M. Mycobacterium tuberculosis CwsA interacts with CrgA and Wag31, and the CrgA-CwsA complex is involved in peptidoglycan synthesis and cell shape determination. J Bacteriol. 2012 Dec;194(23):6398-409. doi: 10.1128/JB.01005-12. Epub 2012 Sep, 21. PMID:23002219 doi:http://dx.doi.org/10.1128/JB.01005-12