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1p1y
From Proteopedia
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|PDB= 1p1y |SIZE=350|CAPTION= <scene name='initialview01'>1p1y</scene>, resolution 2.10Å | |PDB= 1p1y |SIZE=350|CAPTION= <scene name='initialview01'>1p1y</scene>, resolution 2.10Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=MG:MAGNESIUM ION'>MG</scene> | + | |LIGAND= <scene name='pdbligand=BRU:5-BROMO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE'>BRU</scene>, <scene name='pdbligand=CB2:PHOSPHORIC+ACID+MONO-[5-(4-AMINO-5-BROMO-2-OXO-2H-PYRIMIDIN-1-YL)-3,4-DIHYDROXY-TETRAHYDRO-FURAN-2-YLMETHYL]+ESTER'>CB2</scene>, <scene name='pdbligand=DA:2'-DEOXYADENOSINE-5'-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DG:2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p1y OCA], [http://www.ebi.ac.uk/pdbsum/1p1y PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1p1y RCSB]</span> | ||
}} | }} | ||
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[[Category: Paukstelis, P J.]] | [[Category: Paukstelis, P J.]] | ||
[[Category: Seeman, N C.]] | [[Category: Seeman, N C.]] | ||
| - | [[Category: MG]] | ||
[[Category: continuous three-dimensional dna lattice]] | [[Category: continuous three-dimensional dna lattice]] | ||
[[Category: parallel-stranded base pair]] | [[Category: parallel-stranded base pair]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:53:39 2008'' |
Revision as of 19:53, 30 March 2008
| |||||||
| , resolution 2.10Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , , , | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of a continuous three-dimensional DNA lattice from d(GGACAGATGGGAG)
Overview
DNA has proved to be a versatile material for the rational design and assembly of nanometer scale objects. Here we report the crystal structure of a continuous three-dimensional DNA lattice formed by the self-assembly of a DNA 13-mer. The structure consists of stacked layers of parallel helices with adjacent layers linked through parallel-stranded base pairing. The hexagonal lattice geometry contains solvent channels that appear large enough to allow 3'-linked guest molecules into the crystal. We have successfully used these parallel base pairs to design and produce crystals with greatly enlarged solvent channels. This lattice may have applications as a molecular scaffold for structure determination of guest molecules, as a molecular sieve, or in the assembly of molecular electronics. Predictable non-Watson-Crick base pairs, like those described here, may present a new tool in structural DNA nanotechnology.
About this Structure
1P1Y is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
Crystal structure of a continuous three-dimensional DNA lattice., Paukstelis PJ, Nowakowski J, Birktoft JJ, Seeman NC, Chem Biol. 2004 Aug;11(8):1119-26. PMID:15324813
Page seeded by OCA on Sun Mar 30 22:53:39 2008
