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1du9
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1du9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mesobuthus_martensii Mesobuthus martensii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DU9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DU9 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1du9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mesobuthus_martensii Mesobuthus martensii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DU9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DU9 FirstGlance]. <br> | ||
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1du9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1du9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1du9 RCSB], [http://www.ebi.ac.uk/pdbsum/1du9 PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1du9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1du9 OCA], [http://pdbe.org/1du9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1du9 RCSB], [http://www.ebi.ac.uk/pdbsum/1du9 PDBsum]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/KAX91_MESMA KAX91_MESMA]] Blocks small conductance calcium-activated potassium channels (KCNN, SK). Weakly inhibits the Kv7.1/KCNQ1 channel (10 uM of the toxin inhibits currents by 23.3%). Low toxicity by intracerebroventricular injection into mice.<ref>PMID:22511981</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 1du9" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
Revision as of 09:47, 11 September 2015
SOLUTION STRUCTURE OF BMP02, A NATURAL SCORPION TOXIN WHICH BLOCKS APAMIN-SENSITIVE CALCIUM-ACTIVATED POTASSIUM CHANNELS, 25 STRUCTURES
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