1pup

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|PDB= 1pup |SIZE=350|CAPTION= <scene name='initialview01'>1pup</scene>, resolution 1.700&Aring;
|PDB= 1pup |SIZE=350|CAPTION= <scene name='initialview01'>1pup</scene>, resolution 1.700&Aring;
|SITE=
|SITE=
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|LIGAND= <scene name='pdbligand=NH2:AMINO GROUP'>NH2</scene>
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|LIGAND= <scene name='pdbligand=APN:2-AMINOETHYLGLYCINE-CARBONYLMETHYLENE-ADENINE'>APN</scene>, <scene name='pdbligand=CPN:2-AMINOETHYLGLYCINE-CARBONYLMETHYLENE-CYTOSINE'>CPN</scene>, <scene name='pdbligand=GPN:2-AMINOETHYLGLYCINE-CARBONYLMETHYLENE-GUANINE'>GPN</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=TPN:2-AMINOETHYLGLYCINE-CARBONYLMETHYLENE-THYMINE'>TPN</scene>
|ACTIVITY=
|ACTIVITY=
|GENE=
|GENE=
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|DOMAIN=
 +
|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pup OCA], [http://www.ebi.ac.uk/pdbsum/1pup PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1pup RCSB]</span>
}}
}}
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[[Category: Kastrup, J S.]]
[[Category: Kastrup, J S.]]
[[Category: Rasmussen, H.]]
[[Category: Rasmussen, H.]]
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[[Category: NH2]]
 
[[Category: dna analogue]]
[[Category: dna analogue]]
[[Category: double helix]]
[[Category: double helix]]
[[Category: peptide nucleic acid]]
[[Category: peptide nucleic acid]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:29:16 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:04:47 2008''

Revision as of 20:04, 30 March 2008


PDB ID 1pup

Drag the structure with the mouse to rotate
, resolution 1.700Å
Ligands: , , , ,
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE OF A PEPTIDE NUCLEIC ACID (PNA) DUPLEX AT 1.7 ANGSTROMS RESOLUTION


Overview

The crystal structure of a PNA duplex reveals both a right- and a left-handed helix in the unit cell. The helices are wide (28A), large pitched (18bp) with the base pairs perpendicular to the helix axis, thereby demonstrating that PNA besides adapting to oligonucleotide partners also has a unique structure by itself.

About this Structure

1PUP is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

Reference

Crystal structure of a peptide nucleic acid (PNA) duplex at 1.7 A resolution., Rasmussen H, Kastrup JS, Nielsen JN, Nielsen JM, Nielsen PE, Nat Struct Biol. 1997 Feb;4(2):98-101. PMID:9033585

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