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2yjz
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yjz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yjz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yjz RCSB], [http://www.ebi.ac.uk/pdbsum/2yjz PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yjz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yjz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yjz RCSB], [http://www.ebi.ac.uk/pdbsum/2yjz PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/STEA4_RAT STEA4_RAT]] Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Inhibits anchorage-independent cell proliferation. Associated with obesity and insulin-resistance. Involved in inflammatory arthritis, through the regulation of inflammatory cytokines. Play a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 14:16, 24 December 2014
Rat STEAP4 oxidoreductase domain complexed with NADP
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