3mn3

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mn3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mn3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mn3 RCSB], [http://www.ebi.ac.uk/pdbsum/3mn3 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mn3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mn3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mn3 RCSB], [http://www.ebi.ac.uk/pdbsum/3mn3 PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/SNF1_YEAST SNF1_YEAST]] Essential for release from glucose repression. It interacts and has functional relationship to the regulatory protein SNF4. Could phosphorylate CAT8. Phosphorylates histone H3 to form H3S10ph, which promotes H3K14ac formation, and which is required for transcriptional activation through TBP recruitment to the promoters.<ref>PMID:15719021</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 13:19, 25 December 2014

An inhibited conformation for the protein kinase domain of the Saccharomyces cerevisiae AMPK homolog Snf1

3mn3, resolution 2.38Å

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