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3jv3
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jv3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jv3 RCSB], [http://www.ebi.ac.uk/pdbsum/3jv3 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jv3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jv3 RCSB], [http://www.ebi.ac.uk/pdbsum/3jv3 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ITSN1_MOUSE ITSN1_MOUSE]] Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR may involve association with DAB2. Inhibits ARHGAP31 activity toward RAC1. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 09:42, 25 December 2014
Structure of SH3E-DH unit of murine intersectin-1L
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