3ibp
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ibp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ibp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ibp RCSB], [http://www.ebi.ac.uk/pdbsum/3ibp PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ibp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ibp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ibp RCSB], [http://www.ebi.ac.uk/pdbsum/3ibp PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MUKB_ECOLI MUKB_ECOLI]] Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organizes and compacts chromosomes. May achieve or facilitate chromosome segregation by condensation of DNA from both sides of a centrally located replisome during cell division. Stimulates both DNA relaxation and to a lesser extent decatenation activity of topoisomerase IV.<ref>PMID:20921377</ref> <ref>PMID:10660686</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 11:43, 25 December 2014
The Crystal Structure of the Dimerization Domain of Escherichia coli Structural Maintenance of Chromosomes Protein MukB
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Categories: Escherichia coli | Berger, J M | Li, Y | Oakley, M G | Schoeffler, A J | Atp-binding | Cell cycle | Cell division | Chromosome partition | Chromosome segregation | Cohesin | Condensin | Dimerization domain | Dna condensation | Dna-binding | Hinge | Mukb | Nucleotide-binding | Smc | Structural maintenance of chromosome

