3kup
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kup OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3kup RCSB], [http://www.ebi.ac.uk/pdbsum/3kup PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kup OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3kup RCSB], [http://www.ebi.ac.uk/pdbsum/3kup PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CBX3_HUMAN CBX3_HUMAN]] Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 21:52, 25 December 2014
Crystal Structure of the CBX3 Chromo Shadow Domain
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Categories: Homo sapiens | Arrowsmith, C H | Bochkarev, A | Bountra, C | Edwards, A M | Kozieradzki, I | Li, Y | Li, Z | Min, J | Ouyang, H | Structural genomic | Tempel, W | Weigelt, J | Chromatin regulator | Chromo shadow domain | Nucleus | Phosphoprotein | Repressor | Sgc | Transcription | Transcription regulation
