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3k64

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k64 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3k64 RCSB], [http://www.ebi.ac.uk/pdbsum/3k64 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k64 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3k64 RCSB], [http://www.ebi.ac.uk/pdbsum/3k64 PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/FBF2_CAEEL FBF2_CAEEL]] Involved in the control of stem cells and sex determination in the C.elegans hermaphrodite germline. May also play a role in the hermaphrodite germline proliferation and oogenesis. Binds specifically to the regulatory region of fem-3 3'-UTR and mediates the sperm/oocyte switch. Negatively regulates gld-3 expression possibly by directly binding to two sites within the gld-3 isoform B 3'-UTR.<ref>PMID:9393998</ref> <ref>PMID:15454534</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 13:53, 24 December 2014

Crystal structure of FBF-2/fem-3 PME complex

3k64, resolution 2.00Å

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