3q91
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q91 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q91 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q91 RCSB], [http://www.ebi.ac.uk/pdbsum/3q91 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q91 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q91 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q91 RCSB], [http://www.ebi.ac.uk/pdbsum/3q91 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/NUD14_HUMAN NUD14_HUMAN]] Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and ADP-ribose to ribose 5-phosphate and AMP. The physiological substrate is probably UDP-glucose. Poor activity on other substrates such as ADP-glucose, CDP-glucose, GDP-glucose and GDP-mannose. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> |
Revision as of 08:14, 24 December 2014
Crystal Structure of Human Uridine Diphosphate Glucose Pyrophosphatase (NUDT14)
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Categories: Homo sapiens | UDP-sugar diphosphatase | Arrowsmith, C H | Berg, S Van Der | Berglund, H | Bountra, C | Collins, R | Edwards, A M | Ekblad, T | Flodin, S | Flores, A | Graslund, S | Hammarstrom, M | Johansson, I | Karlberg, T | Kol, S | Kotenyova, T | Kouznetsova, E | Moche, M | Nordlund, P | Nyman, T | Persson, C | Structural genomic | Schuler, H | Schutz, P | Siponen, M I | Thorsell, A G | Tresaugues, L | Wahlberg, E | Weigelt, J | Welin, M | Hydrolase | Magnesium binding | Mutt-like | Nudix | Sgc