3qwm
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qwm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qwm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qwm RCSB], [http://www.ebi.ac.uk/pdbsum/3qwm PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qwm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qwm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qwm RCSB], [http://www.ebi.ac.uk/pdbsum/3qwm PDBsum]</span></td></tr> | ||
</table> | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/IQEC1_HUMAN IQEC1_HUMAN]] In addition to accelerate GTP gamma S binding by ARFs of all three classes, it appears to function preferentially as a guanine nucleotide exchange protein for ARF6, mediating internalisation of beta-1 integrin.<ref>PMID:11226253</ref> <ref>PMID:16461286</ref> | ||
+ | == References == | ||
+ | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> |
Revision as of 20:21, 25 December 2014
Crystal Structure of GEP100, the plextrin homology domain of IQ motif and SEC7 domain-containing protein 1 isoform a
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Categories: Homo sapiens | Allerston, C | Arrowsmith, C H | Bountra, C | Chaikuad, A | Delft, F von | Edwards, A | Feller, S | Felletar, I | Filippakopoulos, P | Janning, M | Knapp, S | Krojer, T | Picaud, S | Structural genomic | Sabe, H | Weigelt, J | Alpha-catenin | Arf1 | Arf5 | Arf6 | Egfr | Guanine nucleotide exchange factor | Ph domain | Sgc | Signaling protein