3qik
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qik FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qik OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qik RCSB], [http://www.ebi.ac.uk/pdbsum/3qik PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qik FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qik OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qik RCSB], [http://www.ebi.ac.uk/pdbsum/3qik PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PREX1_HUMAN PREX1_HUMAN]] Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 06:47, 25 December 2014
Crystal structure of the first PDZ domain of PREX1
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Categories: Homo sapiens | Arrowsmith, C H | Bountra, C | Edwards, A M | Li, Y | Park, H | Structural genomic | Shen, L | Tempel, W | Tong, Y | Weigelt, J | Hydrolase regulator | Pdz domain | Sgc
