Ribonuclease

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**[[2z70]], [[2ea1]] - EcRNase I + DNA<br />
**[[2z70]], [[2ea1]] - EcRNase I + DNA<br />
**[[3tsr]] - mRNase I + inhibitor<br />
**[[3tsr]] - mRNase I + inhibitor<br />
 +
 +
*RNase II
 +
 +
**[[2ix0]], [[2id0]] - EcRNase II<br />
 +
**[[2ix1]] - EcRNase II (mutant)<br />
 +
**[[1m58]], [[1km8]], [[1km9]] - BuRNase II - Bullfrog<br />
 +
**[[1bc4]] - BuRNase II - NMR<br />
 +
**[[1m07]] - BuRNase II + DNA<br />
 +
**[[2bex]] - hRNase II + RNase inhibitor protein<br />
 +
**[[2bzz]], [[2c01]], [[2c02]], [[2c05]] - hRNase II + inhibitor<br />
 +
 +
*RNase III
 +
 +
**[[2nue]], [[2nuf]], [[2nug]], [[1yyk]], [[1yyw]], [[4m2z]], [[4m30]] - AaRNase III + RNA - ''Aquifex aeolicus''<br />
 +
**2ez6]], [[1yyo]], [[1yz9]], [[1rc7]] - AaRNase III (mutant) + RNA<br />
 +
**[[1rc5]], [[1i4s]], [[1jfz]] - AaRNase III N terminal<br />
 +
**[[1z5f]] - BuRNase III<br />
 +
**[[2a11]] - MtRNase III - ''Mycobacterium tuberculosis''<br />
 +
**[[1o0w]] - TmRNase III - ''Thermotoga maritima''<br />
 +
**[[1t4n]], [[1t4o]] - yRNase III - yeast - NMR<br />
 +
**[[2lbs]] - yRNase III RNA-binding domain + RNA - NMR<br />
 +
**[[2lup]], [[4oog]] - yRNase III RNA-binding domain + RNA <br />
 +
**[[2luq]] - yRNase III RNA-binding domain <br />
 +
**[[2kb5]] - hRNase III - NMR<br />
 +
**[[1dyt]], [[1qmt]], [[2khx]] - hRNase III <br />
 +
**[[1h1h]] - hRNase III + nucleotide<br />
 +
**[[3n3w]], [[3o2r]] - RNase III nuclease domain - ''Campylobacter jejuni''<br />
 +
 +
*RNase 4
 +
 +
**[[1wdy]] - hRNase 4 <br />
 +
**[[2rnf]], [[1rnf]] - hRNase 4 + nucleotide<br />
 +
**[[1kvz]] - BuRNase 4 - NMR<br />
 +
 +
*RNase 5
 +
 +
**[[1un3]], [[1un4]], [[1un5]], [[1gv7]] - hRNase 5 (mutant)<br />
 +
**[[1h0d]] - hRNase 5 + antibody<br />
 +
**[[3lje]] - ZeRNase 5<br />
 +
 +
*RNase 6
 +
 +
**[[1oj1]], [[1oj8]] - BuRNase 6 + nucleotide<br />
 +
}}
}}

Revision as of 07:52, 21 December 2014

Ribonuclease A (magenta) complex with thymidilic acid DNA tetramer (pink), 1rta

Drag the structure with the mouse to rotate

3D Structures of Ribonuclease

Updated on 21-December-2014

  • RNase I
  • 

 RNase II
  • RNase III
    • 2nue, 2nuf, 2nug, 1yyk, 1yyw, 4m2z, 4m30 - AaRNase III + RNA - Aquifex aeolicus
    • 2ez6, 1yyo, 1yz9, 1rc7 - AaRNase III (mutant) + RNA 

    • 1rc5, 1i4s, 1jfz - AaRNase III N-terminal

    • 1z5f - BuRNase III
    • 2a11 - MtRNase III - Mycobacterium tuberculosis
    • 1o0w - TmRNase III - Thermotoga maritima
      

    • 1t4n, 1t4o - yRNase III – yeast - NMR
    • 2lbs - yRNase III RNA-binding domain + RNA – NMR
    • 2lup, 4oog - yRNase III RNA-binding domain + RNA
    • 2luq - yRNase III RNA-binding domain
    • 2kb5 - hRNase 3 - NMR
      

    • 1dyt, 1qmt - hRNase 3

    • 1h1h - hRNase 3 + nucleotide
      


    • 2khx – hRNase III
    • 3n3w, 3o2r - RNase III nuclease domain – Campylobacter jejuni
  • RNase 4
    • 1wdy - hRNase 4

    • 2rnf, 1rnf - hRNase 4 + nucleotide
      

    • 1kvz - BuRNase 4 - NMR
  • RNase 5
  • RNase 6
  • RNase 7
    • 2hky - hRNase 7 - NMR
  • RNase A
  • RNase B
    • 1rbb – bRNase B
    • 1rbj - bRNase B + tetranucleotide
  • RNase BA
  • RNase D
    • 1yt3 - EcRNase D


  • RNase E
    • 2vmk, 2c4r, 2bx2 - EcRNase E catalytic domain
    • 1slj - EcRNase E S1 domain - NMR
      

    • 1smx, 1sn8 - EcRNase E S1 domain 

    • 2vrt, 2c0b - EcRNase E catalytic domain + RNA
    • 3h8a – EcRNase E recognition domain + enolase
  • RNase F1
    • 1fus, 1fut – GfRNase F1 + nucleotide – Gibberella fujikuroi
    • 1rck, 1rcl - GfRNase F1 - NMR
  • RNase H
  • RNase HI
  • RNase HII
    • 3p83 - AfRNase HII + DNA polymerase sliding clamp - Archaeoglobus fulgidus

    • 1i39, 1i3a - AfRNAse HII

    • 3puf, 3p56, 3p5j - hRNAse H2 subunits α+β+γ 

    • 3kio - mRNase H2 subunits α+β+γ 
- mouse

    • 3o3g - TmRNase HII + DNA
      

    • 3o3f, 3o3h, 4hht - TmRNase HII (mutant) + DNA
    • 2etj - TmRNase HII 

    • 1x1p, 1io2 - TkRNase HII

    • 2dfe, 2dff, 2dfh - TkRNase HII (mutant) - Thermococcus kodakarensis

    • 1eke - RNase HII - Methanocalcococcus jannaschii


  • RNase HIII
    • 2d0a, 2d0b, 2d0c - GsRNase HIII - Geobacillus stearothermophilus


    • 3asm - GsRNase HIII (mutant)
    • 1uax - PhRNase HIII – Pyrococcus horikoshii
    • 3vn5 - AaRNase HIII
  • RNase J
    • 3bk1 - TtRNase J

    • 3bk2 - TtRNase J + nucleotide
    • 3zq4 - BsRNase J1- Bacillus subtilis
  • RNase L
    • 4o1o - pRNase L + oligoadenylate + CMP – pig
    • 4o1p - pRNase L + oligoadenylate + AMPPNP
    • 4oav - hRNase L + oligoadenylate + AMPPCP + RNA
  • RNase LE
    • 1dix - RNase LE - tomato
  • RNase MAR1
    • 1xn4 - RNase MAR1 – Leishmania major
    • 2b34 - RNase MAR1 – Caenorhabditis elegans
  • RNase MS
    • 1rms, 1rds - RNase MS + nucleotide - Aspergillus phoenicis
  • RNase MC1
    • 1v9h, 1j1f, 1j1g - McRNase MC1 (mutant) + nucleotide - Momordica charantia 

    • 1ucg - McRNase MC1 (mutant)
    • 1ucd, 1uca, 1ucc - McRNase MC1 + nucleotide
    • 1bk7 - McRNase MC1


  • RNase NT
  • RNase P
    • 3ok7, 3okb, 3q1q, 3q1r - TmRNase P + TmRNase P RNA + tRNA Phe

    • 1nz0 - TmRNase P

    • 1d6t - RNase P - Staphylococcus aureus
    • 2a64 - BsRNase P (mutant) - Bacillus stearothermophilus


    • 1a6f, 1nbs, 2jg4 - BsRNase P (mutant)
    • 1ts9, 1tsf – AfRNase P
    • 1u9s – RNase P – synthetic
    • 2avs - PfRNase P (mutant) – Pyrococcus furiosus
    • 2k3r, 2ki7 - PfRNase P
    • 2ljp – EcRNase P
    • 2av5 - PhRNase P component 2
    • 1x0t - PhRNase P component 4
    • 2zae - PhRNase P component 1 and 4
    • 2czv - PhRNase P component 2 (mutant) and 3
    • 2cvz, 2zae – PhRNase P
    • 3iab – yRNase P subunits POP6 POP7 + RNase MRP P3 domain
  • RNase PH
    • 3dd6 - RNase PH - Bacillus anthracis

    • 1oyp, 1oyr, 1oys - BsRNase PH 

    • 1r6l, 1r6m - PaRNase PH - Pseudomonas aeruginosa

    • 3b4t - MtRNase PH - Mycobacterium tuberculosis 

    • 1udn - AaRNase PH

    • 1udo, 1udq, 1uds - AaRNase PH (mutant)


  • RNase RH
    • 1bol – Rhizopus niveus
  • RNase S
  • RNase S3
    • 1iqq - RNase S3 - Japanese pear
  • RNase SA
  • RNase SA2
  • RNase SA3
  • RNase SF11
    • 1ioo - RNase SF11 - Nicotiana alata


  • RNase T
  • RNase T1
  • RNase T2
  • RNase U2
    • 3agn, 3ago, 3ahw - UsRNase U2 + AMP - Ustilago sphaerogena

    • 1rtu - UsRNase U2
  • RNase U2B
  • RNase Z
  • α-sarcin
    • 1de3 - αsRNase – Aspergillus giganteus
    • 1r4y - αsRNase (mutant)
  • Oligoribonuclease
    • 2igi, 1yta – EcORNase
    • 2gbz - ORNase - Xanthomonas campestris
    • 1j9a - ORNase - Haemophilus influenzae
    • 3tr8 – ORNase – Coxiella burnetii
  • Polynucleotide Phosphorylase
    • 3cdi - EcPNPase
    • 3gll - EcPNPase core
    • 3cdj - EcPNPase C-terminal truncated
    • 1e3h, 1e3p - PNPase - Streptomyces antibioticus
    • 3gcm, 3gme, 3h1c - EcPNPase + RNase E recognition domain
    • 3h36 - PNPase fragment - Streptococcus mutans
  • Binase
  • Poly(A)-specific RNase
    • 1ug8 – mParn R3H domain - NMR
    • 1whv – mParn RNA-binding domain - NMR
    • 2rok - mParn CAP-binding domain - NMR
    • 3d45 - mParn + nucleotide
    • 2a1s - hParn
    • 2a1r, 3ctr – hParn + nucleotide
    • 2zpo – RNase – Chelonia mydas
    • 3a4y, 3idz, 3ie0, 3ie2 – TtRNase (mutant) – Thermus thermophilus
    • 3iek - TtRNase
    • 3ie1, 3iem - TtRNase (mutant) + RNA
    • 3iel - TtRNase + nucleotide
    • 4b8a – yRNase pop2 + cell division cycle protein 39
    • 4b8c – yRNase pop2 + cell division cycle protein 39 + CCR4

}}

References

  1. ↑ Birdsall DL, McPherson A. Crystal structure disposition of thymidylic acid tetramer in complex with ribonuclease A. J Biol Chem. 1992 Nov 5;267(31):22230-6. PMID:1429575
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