Ribonuclease

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**[[1oj1]], [[1oj8]] - BuRNase 6 + nucleotide<br />
**[[1oj1]], [[1oj8]] - BuRNase 6 + nucleotide<br />
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*RNase 7
 +
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**[[2hky]] - hRNase 7 - NMR <br />
 +
 +
*RNase A
 +
 +
**[[1rra]] - RNase A - rat<br />
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**[[44j5z]], [[4j60]], [[4j61]], [[4j62]], [[4j63]], [[4j64]], [[4j65]], [[4j66]], [[4j67]], [[4j68]], [[4j69]], [[4j6a]], [[4mxf]] - bRNase A <br />
 +
**[[4k7m]] - bRNase A (mutant)<br />
 +
**[[2aas]] - bRNase A - NMR<br />
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**[[4kxh]] - hRNase A <br />
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**[[2e33]] - bRNase A + F-box only protein 2<br />
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**[[4l55]] - bRNase A + aziru<br />
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*RNase B
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 +
**[[1rbb]] - bRNase B <br />
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**[[1rbj]] - bRNase B + tetranucleotide <br />
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*RNase BA
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**[[1x1u]], [[1x1x]], [[1x1y]], [[1b27]], [[1b2u]], [[1b3s]], [[1x1w]] - BaRNase BA + barstar (mutant) - ''Bacillus amyloliquefaciens''<br />
 +
**[[3da7]], [[1brs]], [[1bgs]] - BaRNase BA + barstar <br />
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**[[1b2s]], [[2za4]] - BaRNase BA (mutant) + barstar (mutant) <br />
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**[[1brn]], [[2kf5]], [[2kf6]], [[1rnb]] - BaRNase BA + nucleotide<br />
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**[[3kch]], [[2f4y]], [[2f56]], [[2f5m]], [[2f5w]] - BaRNase BA crosslinked<br />
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**[[2kf3]], [[2kf4]], [[1fw7]], [[1bnr]] - BaRNase BA - NMR<br />
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**[[1yvs]], [[1b2x]], [[1a2p]], [[1bni]], [[1bnj]] - BaRNase BA <br />
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**[[1b20]], [[1b21]], [[1b2z]], [[1bne]], [[1bnf]], [[1bng]], [[1brh]], [[1bri]], [[1brj]], [[1brk]], [[1bns]], [[1brg]], [[1bsa]], [[1bsb]], [[1bsc]], [[1bsd]], [[1bse]], [[1bna]], [[1bao]] - BaRNase BA (mutant)<br />
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*RAase D
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**[[1yt3]] - EcRNase D<br />
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*RNase E
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**[[2vmk]], [[2c4r]], [[2bx2]] - EcRNase E catalytic domain<br />
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**[[1slj]] - EcRNase E S1 domain - NMR<br />
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**[[1smx]], [[1sn8]] - EcRNase E S1 domain <br />
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**[[2vrt]], [[2c0b]] - EcRNase E catalytic domain + RNA<br />
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**[[3h8a]] - EcRNase E recognition domain + enolase<br />
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*RNase F1
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**[[1fus]], [[1fut]] - GfRNase F1 + nucleotide - ''Gibberella fujikuroi''<br />
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**[[1rck]], [[1rci]] - GfRNase F1 - NMR<br />
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*RNase H
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**[[3h7i]], [[3h8s]], [[3h8w]] - T4RNase H (mutant) - Enterobacteria phage T4<br />
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**[[2ihn]] - T4RNase H (mutant) + DNA<br />
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**[[3h8j]], [[1tfr]] - T4RNase H <br />
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**[[4e89]] - RNase H - XMRV<br />
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**[[2rpi]], [[1ril]] - TtRNase H - ''Thermus thermophilus''<br />
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**[[1rbr]], [[1rbs]], [[1rbt]], [[1rbu]], [[1rbv]], [[2rn2]] - EcRNase H <br />
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**[[1lav]], [[1law]], [[1rda]], [[1rdb]], [[1rdc]] - EcRNase H (mutant) <br />
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**[[1jl2]] - EcRNase H/TtRNase H <br />
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**[[3d0p]], [[3ey1]], [[3i8d]] - BhRNase H (mutant) + DNA - ''Bacillus halodurans''<br />
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**[[1zbf]] - BhRNase H (mutant) <br />
 +
**[[2r7y]], [[2g8f]], [[2g8h]], [[2g8i]], [[2g8k]], [[2g8u]], [[2g8v]], [[2g8w]], [[1zbi]], [[1zbl]], [[3twh]], [[3uld]] - BhRNase H (mutant) + RNA + DNA<br />
 +
**[[4htu]], [[4hue]], [[4huf]], [[4hug]] - BhRNase H + DNA<br />
 +
**[[4ibn]] - uRNase H - uncultured<br />
 +
**[[4h8k]] - uRNase H + RNA + DNA<br />
}}
}}

Revision as of 07:53, 21 December 2014

Ribonuclease A (magenta) complex with thymidilic acid DNA tetramer (pink), 1rta

Drag the structure with the mouse to rotate

3D Structures of Ribonuclease

Updated on 21-December-2014

  • RNase I
  • 

 RNase II
  • RNase III
    • 2nue, 2nuf, 2nug, 1yyk, 1yyw, 4m2z, 4m30 - AaRNase III + RNA - Aquifex aeolicus
    • 2ez6, 1yyo, 1yz9, 1rc7 - AaRNase III (mutant) + RNA 

    • 1rc5, 1i4s, 1jfz - AaRNase III N-terminal

    • 1z5f - BuRNase III
    • 2a11 - MtRNase III - Mycobacterium tuberculosis
    • 1o0w - TmRNase III - Thermotoga maritima
      

    • 1t4n, 1t4o - yRNase III – yeast - NMR
    • 2lbs - yRNase III RNA-binding domain + RNA – NMR
    • 2lup, 4oog - yRNase III RNA-binding domain + RNA
    • 2luq - yRNase III RNA-binding domain
    • 2kb5 - hRNase 3 - NMR
      

    • 1dyt, 1qmt - hRNase 3

    • 1h1h - hRNase 3 + nucleotide
      


    • 2khx – hRNase III
    • 3n3w, 3o2r - RNase III nuclease domain – Campylobacter jejuni
  • RNase 4
    • 1wdy - hRNase 4

    • 2rnf, 1rnf - hRNase 4 + nucleotide
      

    • 1kvz - BuRNase 4 - NMR
  • RNase 5
  • RNase 6
  • RNase 7
    • 2hky - hRNase 7 - NMR
  • RNase A
  • RNase B
    • 1rbb – bRNase B
    • 1rbj - bRNase B + tetranucleotide
  • RNase BA
  • RNase D
    • 1yt3 - EcRNase D


  • RNase E
    • 2vmk, 2c4r, 2bx2 - EcRNase E catalytic domain
    • 1slj - EcRNase E S1 domain - NMR
      

    • 1smx, 1sn8 - EcRNase E S1 domain 

    • 2vrt, 2c0b - EcRNase E catalytic domain + RNA
    • 3h8a – EcRNase E recognition domain + enolase
  • RNase F1
    • 1fus, 1fut – GfRNase F1 + nucleotide – Gibberella fujikuroi
    • 1rck, 1rcl - GfRNase F1 - NMR
  • RNase H
  • RNase HI
  • RNase HII
    • 3p83 - AfRNase HII + DNA polymerase sliding clamp - Archaeoglobus fulgidus

    • 1i39, 1i3a - AfRNAse HII

    • 3puf, 3p56, 3p5j - hRNAse H2 subunits α+β+γ 

    • 3kio - mRNase H2 subunits α+β+γ 
- mouse

    • 3o3g - TmRNase HII + DNA
      

    • 3o3f, 3o3h, 4hht - TmRNase HII (mutant) + DNA
    • 2etj - TmRNase HII 

    • 1x1p, 1io2 - TkRNase HII

    • 2dfe, 2dff, 2dfh - TkRNase HII (mutant) - Thermococcus kodakarensis

    • 1eke - RNase HII - Methanocalcococcus jannaschii


  • RNase HIII
    • 2d0a, 2d0b, 2d0c - GsRNase HIII - Geobacillus stearothermophilus


    • 3asm - GsRNase HIII (mutant)
    • 1uax - PhRNase HIII – Pyrococcus horikoshii
    • 3vn5 - AaRNase HIII
  • RNase J
    • 3bk1 - TtRNase J

    • 3bk2 - TtRNase J + nucleotide
    • 3zq4 - BsRNase J1- Bacillus subtilis
  • RNase L
    • 4o1o - pRNase L + oligoadenylate + CMP – pig
    • 4o1p - pRNase L + oligoadenylate + AMPPNP
    • 4oav - hRNase L + oligoadenylate + AMPPCP + RNA
  • RNase LE
    • 1dix - RNase LE - tomato
  • RNase MAR1
    • 1xn4 - RNase MAR1 – Leishmania major
    • 2b34 - RNase MAR1 – Caenorhabditis elegans
  • RNase MS
    • 1rms, 1rds - RNase MS + nucleotide - Aspergillus phoenicis
  • RNase MC1
    • 1v9h, 1j1f, 1j1g - McRNase MC1 (mutant) + nucleotide - Momordica charantia 

    • 1ucg - McRNase MC1 (mutant)
    • 1ucd, 1uca, 1ucc - McRNase MC1 + nucleotide
    • 1bk7 - McRNase MC1


  • RNase NT
  • RNase P
    • 3ok7, 3okb, 3q1q, 3q1r - TmRNase P + TmRNase P RNA + tRNA Phe

    • 1nz0 - TmRNase P

    • 1d6t - RNase P - Staphylococcus aureus
    • 2a64 - BsRNase P (mutant) - Bacillus stearothermophilus


    • 1a6f, 1nbs, 2jg4 - BsRNase P (mutant)
    • 1ts9, 1tsf – AfRNase P
    • 1u9s – RNase P – synthetic
    • 2avs - PfRNase P (mutant) – Pyrococcus furiosus
    • 2k3r, 2ki7 - PfRNase P
    • 2ljp – EcRNase P
    • 2av5 - PhRNase P component 2
    • 1x0t - PhRNase P component 4
    • 2zae - PhRNase P component 1 and 4
    • 2czv - PhRNase P component 2 (mutant) and 3
    • 2cvz, 2zae – PhRNase P
    • 3iab – yRNase P subunits POP6 POP7 + RNase MRP P3 domain
  • RNase PH
    • 3dd6 - RNase PH - Bacillus anthracis

    • 1oyp, 1oyr, 1oys - BsRNase PH 

    • 1r6l, 1r6m - PaRNase PH - Pseudomonas aeruginosa

    • 3b4t - MtRNase PH - Mycobacterium tuberculosis 

    • 1udn - AaRNase PH

    • 1udo, 1udq, 1uds - AaRNase PH (mutant)


  • RNase RH
    • 1bol – Rhizopus niveus
  • RNase S
  • RNase S3
    • 1iqq - RNase S3 - Japanese pear
  • RNase SA
  • RNase SA2
  • RNase SA3
  • RNase SF11
    • 1ioo - RNase SF11 - Nicotiana alata


  • RNase T
  • RNase T1
  • RNase T2
  • RNase U2
    • 3agn, 3ago, 3ahw - UsRNase U2 + AMP - Ustilago sphaerogena

    • 1rtu - UsRNase U2
  • RNase U2B
  • RNase Z
  • α-sarcin
    • 1de3 - αsRNase – Aspergillus giganteus
    • 1r4y - αsRNase (mutant)
  • Oligoribonuclease
    • 2igi, 1yta – EcORNase
    • 2gbz - ORNase - Xanthomonas campestris
    • 1j9a - ORNase - Haemophilus influenzae
    • 3tr8 – ORNase – Coxiella burnetii
  • Polynucleotide Phosphorylase
    • 3cdi - EcPNPase
    • 3gll - EcPNPase core
    • 3cdj - EcPNPase C-terminal truncated
    • 1e3h, 1e3p - PNPase - Streptomyces antibioticus
    • 3gcm, 3gme, 3h1c - EcPNPase + RNase E recognition domain
    • 3h36 - PNPase fragment - Streptococcus mutans
  • Binase
  • Poly(A)-specific RNase
    • 1ug8 – mParn R3H domain - NMR
    • 1whv – mParn RNA-binding domain - NMR
    • 2rok - mParn CAP-binding domain - NMR
    • 3d45 - mParn + nucleotide
    • 2a1s - hParn
    • 2a1r, 3ctr – hParn + nucleotide
    • 2zpo – RNase – Chelonia mydas
    • 3a4y, 3idz, 3ie0, 3ie2 – TtRNase (mutant) – Thermus thermophilus
    • 3iek - TtRNase
    • 3ie1, 3iem - TtRNase (mutant) + RNA
    • 3iel - TtRNase + nucleotide
    • 4b8a – yRNase pop2 + cell division cycle protein 39
    • 4b8c – yRNase pop2 + cell division cycle protein 39 + CCR4

}}

References

  1. ↑ Birdsall DL, McPherson A. Crystal structure disposition of thymidylic acid tetramer in complex with ribonuclease A. J Biol Chem. 1992 Nov 5;267(31):22230-6. PMID:1429575
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