4c45

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c45 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4c45 RCSB], [http://www.ebi.ac.uk/pdbsum/4c45 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c45 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4c45 RCSB], [http://www.ebi.ac.uk/pdbsum/4c45 PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PHS2_HUMAN PHS2_HUMAN]] Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2 (By similarity). Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity.
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</StructureSection>
</StructureSection>

Revision as of 01:42, 25 December 2014

Crystal structure of human pterin-4-alpha-carbinolamine dehydratase 2 (PCBD2)

4c45, resolution 1.45Å

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