1rif
From Proteopedia
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|PDB= 1rif |SIZE=350|CAPTION= <scene name='initialview01'>1rif</scene>, resolution 2.Å | |PDB= 1rif |SIZE=350|CAPTION= <scene name='initialview01'>1rif</scene>, resolution 2.Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand= | + | |LIGAND= <scene name='pdbligand=AU:GOLD+ION'>AU</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> |
|ACTIVITY= | |ACTIVITY= | ||
| - | |GENE= UVSW, DAR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id= | + | |GENE= UVSW, DAR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 Enterobacteria phage T4]) |
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rif FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rif OCA], [http://www.ebi.ac.uk/pdbsum/1rif PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1rif RCSB]</span> | ||
}} | }} | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1RIF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/ | + | 1RIF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RIF OCA]. |
==Reference== | ==Reference== | ||
The crystal structure of the UvsW helicase from bacteriophage T4., Sickmier EA, Kreuzer KN, White SW, Structure. 2004 Apr;12(4):583-92. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15062081 15062081] | The crystal structure of the UvsW helicase from bacteriophage T4., Sickmier EA, Kreuzer KN, White SW, Structure. 2004 Apr;12(4):583-92. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15062081 15062081] | ||
| - | [[Category: | + | [[Category: Enterobacteria phage t4]] |
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Kreuzer, K N.]] | [[Category: Kreuzer, K N.]] | ||
[[Category: Sickmier, E A.]] | [[Category: Sickmier, E A.]] | ||
[[Category: White, S W.]] | [[Category: White, S W.]] | ||
| - | [[Category: AU]] | ||
| - | [[Category: MG]] | ||
[[Category: bacteriophage]] | [[Category: bacteriophage]] | ||
[[Category: helicase]] | [[Category: helicase]] | ||
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[[Category: uvsw]] | [[Category: uvsw]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:28:35 2008'' |
Revision as of 20:28, 30 March 2008
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| , resolution 2.Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , | ||||||
| Gene: | UVSW, DAR (Enterobacteria phage T4) | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of the UvsW helicase from Bacteriophage T4
Overview
In bacteriophage T4, the WXY system repairs DNA damage by a process that involves homologous recombination. This system comprises three proteins, the RecA-like recombination protein UvsX, a recombination mediator protein UvsY, and a helicase UvsW. Here we report the 2.0 A resolution crystal structure of the N-terminal two domains of the UvsW helicase (UvsWNF; residues 1-282). The structure reveals a typical helicase RecA-like domain linked to a small N-terminal alpha/beta domain that likely binds the nucleic acid substrate. The missing C-terminal portion of UvsW almost certainly corresponds to the second RecA-like domain typically found in monomeric helicases. The putative substrate binding domain is unique within the known helicase structures, and it resembles the novel "double-wing" DNA binding domain from the phage T4 MotA transcription factor that mediates the expression of T4 middle genes. The functional implications of this homology for the role of UvsW in T4 DNA metabolism are discussed.
About this Structure
1RIF is a Single protein structure of sequence from Enterobacteria phage t4. Full crystallographic information is available from OCA.
Reference
The crystal structure of the UvsW helicase from bacteriophage T4., Sickmier EA, Kreuzer KN, White SW, Structure. 2004 Apr;12(4):583-92. PMID:15062081
Page seeded by OCA on Sun Mar 30 23:28:35 2008
Categories: Enterobacteria phage t4 | Single protein | Kreuzer, K N. | Sickmier, E A. | White, S W. | Bacteriophage | Helicase | Recg | Sf2 | T4 | Uvsw
