4bhp
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bhp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bhp RCSB], [http://www.ebi.ac.uk/pdbsum/4bhp PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bhp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bhp RCSB], [http://www.ebi.ac.uk/pdbsum/4bhp PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CRP_ECOLI CRP_ECOLI]] This protein complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons. The protein induces a severe bend in the DNA. Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP.<ref>PMID:2982847</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 21:17, 24 December 2014
A structural model of CAP mutant (T127L and S128I) in cGMP-bound state
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