4dl1

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{{Large structure}}
==Crystal Structure of human Myeloperoxidase with covalent thioxanthine analog==
==Crystal Structure of human Myeloperoxidase with covalent thioxanthine analog==
<StructureSection load='4dl1' size='340' side='right' caption='[[4dl1]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='4dl1' size='340' side='right' caption='[[4dl1]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Myeloperoxidase Myeloperoxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.2.2 1.11.2.2] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Myeloperoxidase Myeloperoxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.2.2 1.11.2.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dl1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4dl1 RCSB], [http://www.ebi.ac.uk/pdbsum/4dl1 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dl1 OCA], [http://pdbe.org/4dl1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4dl1 RCSB], [http://www.ebi.ac.uk/pdbsum/4dl1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4dl1 ProSAT]</span></td></tr>
</table>
</table>
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{{Large structure}}
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/PERM_HUMAN PERM_HUMAN]] Defects in MPO are the cause of myeloperoxidase deficiency (MPOD) [MIM:[http://omim.org/entry/254600 254600]]. A disorder characterized by decreased myeloperoxidase activity in neutrophils and monocytes that results in disseminated candidiasis.<ref>PMID:8142659</ref> <ref>PMID:7904599</ref> <ref>PMID:8621627</ref> <ref>PMID:9637725</ref> <ref>PMID:9354683</ref>
[[http://www.uniprot.org/uniprot/PERM_HUMAN PERM_HUMAN]] Defects in MPO are the cause of myeloperoxidase deficiency (MPOD) [MIM:[http://omim.org/entry/254600 254600]]. A disorder characterized by decreased myeloperoxidase activity in neutrophils and monocytes that results in disseminated candidiasis.<ref>PMID:8142659</ref> <ref>PMID:7904599</ref> <ref>PMID:8621627</ref> <ref>PMID:9637725</ref> <ref>PMID:9354683</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4dl1" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
*[[Myeloperoxidase|Myeloperoxidase]]
*[[Myeloperoxidase|Myeloperoxidase]]
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*[[Sandbox WWC11|Sandbox WWC11]]
== References ==
== References ==
<references/>
<references/>

Revision as of 02:04, 5 August 2016

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Crystal Structure of human Myeloperoxidase with covalent thioxanthine analog

4dl1, resolution 2.00Å

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