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4ere

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==crystal structure of MDM2 (17-111) in complex with compound 23==
==crystal structure of MDM2 (17-111) in complex with compound 23==
<StructureSection load='4ere' size='340' side='right' caption='[[4ere]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='4ere' size='340' side='right' caption='[[4ere]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4ere]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ERE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ERE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4ere]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ERE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ERE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0R2:[(3R,5R,6S)-1-[(2S)-1-TERT-BUTOXY-1-OXOBUTAN-2-YL]-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-2-OXOPIPERIDIN-3-YL]ACETIC+ACID'>0R2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0R2:[(3R,5R,6S)-1-[(2S)-1-TERT-BUTOXY-1-OXOBUTAN-2-YL]-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-2-OXOPIPERIDIN-3-YL]ACETIC+ACID'>0R2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4erf|4erf]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4erf|4erf]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MDM2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MDM2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ere FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ere OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ere RCSB], [http://www.ebi.ac.uk/pdbsum/4ere PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ere FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ere OCA], [http://pdbe.org/4ere PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ere RCSB], [http://www.ebi.ac.uk/pdbsum/4ere PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ere ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4ere" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Human]]
[[Category: Huang, X]]
[[Category: Huang, X]]
[[Category: Ligase-ligase inhibitor complex]]
[[Category: Ligase-ligase inhibitor complex]]

Revision as of 19:46, 5 August 2016

crystal structure of MDM2 (17-111) in complex with compound 23

4ere, resolution 1.80Å

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