We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.
4igz
From Proteopedia
(Difference between revisions)
| Line 7: | Line 7: | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4igz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4igz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4igz RCSB], [http://www.ebi.ac.uk/pdbsum/4igz PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4igz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4igz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4igz RCSB], [http://www.ebi.ac.uk/pdbsum/4igz PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SRBS2_HUMAN SRBS2_HUMAN]] Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.<ref>PMID:9211900</ref> <ref>PMID:12475393</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 15:37, 25 December 2014
Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2
| |||||||||||
Categories: Homo sapiens | Arrowsmith, C H | Bakkouri, M El | Bountra, C | Edwards, A M | Gu, J | Huang, H | Liu, K | Liu, Y | Min, J | Structural genomic | Sidhu, S S | Tempel, W | Protein binding | Sgc | Sh3 | Src homology 3 domain
