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4i9o

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i9o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4i9o RCSB], [http://www.ebi.ac.uk/pdbsum/4i9o PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i9o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4i9o RCSB], [http://www.ebi.ac.uk/pdbsum/4i9o PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CBP_MOUSE CBP_MOUSE]] Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1 in the presence of EP300 (By similarity).<ref>PMID:10207073</ref> <ref>PMID:11701890</ref> <ref>PMID:15220471</ref> <ref>PMID:16287980</ref>
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

Revision as of 18:09, 25 December 2014

Crystal Structure of GACKIX L664C Tethered to 1-10

4i9o, resolution 2.00Å

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