4ilh

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ilh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ilh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ilh RCSB], [http://www.ebi.ac.uk/pdbsum/4ilh PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ilh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ilh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ilh RCSB], [http://www.ebi.ac.uk/pdbsum/4ilh PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PRP8_YEAST PRP8_YEAST]] Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing. This protein is associated with snRNP U5. Has a role in branch site-3' splice site selection. Associates with the branch site-3' splice 3'-exon region. Also has a role in cell cycle.<ref>PMID:2835658</ref> <ref>PMID:9150140</ref> <ref>PMID:12773561</ref> <ref>PMID:18779563</ref> [[http://www.uniprot.org/uniprot/AAR2_YEAST AAR2_YEAST]] Involved in splicing pre-mRNA of the A1 cistron and other genes that are important for cell growth.
==See Also==
==See Also==
*[[Pre-mRNA-splicing factor|Pre-mRNA-splicing factor]]
*[[Pre-mRNA-splicing factor|Pre-mRNA-splicing factor]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>

Revision as of 07:37, 24 December 2014

Crystal structure of an Aar2p C-terminal deletion mutant in conplex with Prp8p RNaseH

4ilh, resolution 1.85Å

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