4k2p
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k2p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k2p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k2p RCSB], [http://www.ebi.ac.uk/pdbsum/4k2p PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k2p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k2p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k2p RCSB], [http://www.ebi.ac.uk/pdbsum/4k2p PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TIAM1_HUMAN TIAM1_HUMAN]] Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 21:55, 25 December 2014
The Structure of a Quintuple Mutant of the Tiam1 PH-CC-Ex Domain
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