1sfo
From Proteopedia
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|PDB= 1sfo |SIZE=350|CAPTION= <scene name='initialview01'>1sfo</scene>, resolution 3.61Å | |PDB= 1sfo |SIZE=350|CAPTION= <scene name='initialview01'>1sfo</scene>, resolution 3.61Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand= | + | |LIGAND= <scene name='pdbligand=A:ADENOSINE-5'-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5'-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=DA:2'-DEOXYADENOSINE-5'-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5'-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=G:GUANOSINE-5'-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=U:URIDINE-5'-MONOPHOSPHATE'>U</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> |
| - | |ACTIVITY= [http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span> |
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY=[[1r9s|1R9S]], [[1r9t|1R9T]] | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sfo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sfo OCA], [http://www.ebi.ac.uk/pdbsum/1sfo PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1sfo RCSB]</span> | ||
}} | }} | ||
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[[Category: Kornberg, R D.]] | [[Category: Kornberg, R D.]] | ||
[[Category: Westover, K D.]] | [[Category: Westover, K D.]] | ||
| - | [[Category: MG]] | ||
| - | [[Category: ZN]] | ||
[[Category: dna]] | [[Category: dna]] | ||
[[Category: molecular machine]] | [[Category: molecular machine]] | ||
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[[Category: transcription]] | [[Category: transcription]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:41:25 2008'' |
Revision as of 20:41, 30 March 2008
| |||||||
| , resolution 3.61Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , , , , , , , , | ||||||
| Activity: | DNA-directed RNA polymerase, with EC number 2.7.7.6 | ||||||
| Related: | 1R9S, 1R9T
| ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX
Overview
The structure of an RNA polymerase II-transcribing complex has been determined in the posttranslocation state, with a vacancy at the growing end of the RNA-DNA hybrid helix. At the opposite end of the hybrid helix, the RNA separates from the template DNA. This separation of nucleic acid strands is brought about by interaction with a set of proteins loops in a strand/loop network. Formation of the network must occur in the transition from abortive initiation to promoter escape.
About this Structure
1SFO is a Protein complex structure of sequences from Saccharomyces cerevisiae. This structure supersedes the now removed PDB entry 1R9R. Full crystallographic information is available from OCA.
Reference
Structural basis of transcription: separation of RNA from DNA by RNA polymerase II., Westover KD, Bushnell DA, Kornberg RD, Science. 2004 Feb 13;303(5660):1014-6. PMID:14963331
Page seeded by OCA on Sun Mar 30 23:41:25 2008
