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4k2o

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k2o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k2o RCSB], [http://www.ebi.ac.uk/pdbsum/4k2o PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k2o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k2o RCSB], [http://www.ebi.ac.uk/pdbsum/4k2o PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/TIAM1_HUMAN TIAM1_HUMAN]] Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA.
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

Revision as of 01:14, 25 December 2014

The Structure of a Triple Mutant of the Tiam1 PH-CC-Ex Domain

4k2o, resolution 2.15Å

Drag the structure with the mouse to rotate

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