1siz
From Proteopedia
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|PDB= 1siz |SIZE=350|CAPTION= <scene name='initialview01'>1siz</scene>, resolution 2.25Å | |PDB= 1siz |SIZE=350|CAPTION= <scene name='initialview01'>1siz</scene>, resolution 2.25Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=3CO:COBALT+(III)+ION'>3CO</scene> | + | |LIGAND= <scene name='pdbligand=3CO:COBALT+(III)+ION'>3CO</scene>, <scene name='pdbligand=F3S:FE3-S4+CLUSTER'>F3S</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= FDXA, PF1909 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 Pyrococcus furiosus]) | |GENE= FDXA, PF1909 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 Pyrococcus furiosus]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY=[[1sj1|1SJ1]] | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1siz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1siz OCA], [http://www.ebi.ac.uk/pdbsum/1siz PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1siz RCSB]</span> | ||
}} | }} | ||
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[[Category: Harris, P.]] | [[Category: Harris, P.]] | ||
[[Category: Nielsen, M S.]] | [[Category: Nielsen, M S.]] | ||
| - | [[Category: 3CO]] | ||
| - | [[Category: F3S]] | ||
[[Category: dimer]] | [[Category: dimer]] | ||
[[Category: iron-sulfur cluster]] | [[Category: iron-sulfur cluster]] | ||
[[Category: thermostability]] | [[Category: thermostability]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:42:38 2008'' |
Revision as of 20:42, 30 March 2008
| |||||||
| , resolution 2.25Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , | ||||||
| Gene: | FDXA, PF1909 (Pyrococcus furiosus) | ||||||
| Related: | 1SJ1
| ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of the [Fe3S4]-ferredoxin from the hyperthermophilic archaeon Pyrococcus furiosus
Overview
The structure of [Fe(3)S(4)]-ferredoxin from the hyperthermophilic archaeon Pyrococcus furiosus has been determined to 1.5 A resolution from a crystal belonging to space group P2(1) with two molecules in the asymmetric unit. The structure has been solved with molecular replacement by use of the ferredoxin from Thermotoga maritima. The fold is similar to that of related monocluster ferredoxins and contains two double-stranded antiparallel beta-sheets and two alpha-helices. The hydrophobic interaction between Trp2 and Tyr46 is confirmed, linking the C-terminus to the longer alpha-helix. The structure contains a double-conformation disulfide bond existing in a left-handed and a right-handed spiral conformation. The crystal packing reveals a beta-sheet interaction, which supports the suggestion that P. furiosus ferredoxin is a functional dimer. The extraordinary thermostability of P. furiosus ferredoxin is further discussed.
About this Structure
1SIZ is a Single protein structure of sequence from Pyrococcus furiosus. Full crystallographic information is available from OCA.
Reference
The 1.5 A resolution crystal structure of [Fe3S4]-ferredoxin from the hyperthermophilic archaeon Pyrococcus furiosus., Nielsen MS, Harris P, Ooi BL, Christensen HE, Biochemistry. 2004 May 11;43(18):5188-94. PMID:15122884
Page seeded by OCA on Sun Mar 30 23:42:38 2008
