We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.
2xrf
From Proteopedia
(Difference between revisions)
| Line 7: | Line 7: | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xrf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xrf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xrf RCSB], [http://www.ebi.ac.uk/pdbsum/2xrf PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xrf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xrf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xrf RCSB], [http://www.ebi.ac.uk/pdbsum/2xrf PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/UPP2_HUMAN UPP2_HUMAN]] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 21:37, 24 December 2014
Crystal structure of human uridine phosphorylase 2
| |||||||||||
Categories: Human | Uridine phosphorylase | Arrowsmith, C H | Berg, S Van Der | Berglund, H | Bountra, C | Collins, R | Edwards, A M | Flodin, S | Flores, A | Graslund, S | Hammarstrom, M | Johansson, I | Karlberg, T | Kol, S | Kotenyova, T | Kouznetsova, E | Moche, M | Nordlund, P | Nyman, T | Persson, C | Schuler, H | Schutz, P | Siponen, M I | Thorsell, A G | Tresaugues, L | Wahlberg, E | Weigelt, J | Welin, M | Transferase
