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4iio

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4iio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4iio RCSB], [http://www.ebi.ac.uk/pdbsum/4iio PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4iio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4iio RCSB], [http://www.ebi.ac.uk/pdbsum/4iio PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ITSN2_HUMAN ITSN2_HUMAN]] Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs). Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR).<ref>PMID:19458185</ref> <ref>PMID:22648170</ref>
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== References ==
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<references/>
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</StructureSection>
</StructureSection>

Revision as of 06:40, 25 December 2014

Crystal Structure of the Second SH3 Domain of ITSN2 Bound with a Synthetic Peptide

4iio, resolution 1.70Å

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