4n0w
From Proteopedia
(Difference between revisions)
| Line 9: | Line 9: | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4n0w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n0w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4n0w RCSB], [http://www.ebi.ac.uk/pdbsum/4n0w PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4n0w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n0w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4n0w RCSB], [http://www.ebi.ac.uk/pdbsum/4n0w PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/B4ECY9_BURCJ B4ECY9_BURCJ]] Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity).[HAMAP-Rule:MF_00051] | ||
==See Also== | ==See Also== | ||
Revision as of 05:41, 25 December 2014
X-ray crystal structure of a serine hydroxymethyltransferase from Burkholderia cenocepacia with covalently attached pyridoxal phosphate
| |||||||||||
