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1wqk
From Proteopedia
(Difference between revisions)
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wqk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wqk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wqk RCSB], [http://www.ebi.ac.uk/pdbsum/1wqk PDBsum]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wqk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wqk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wqk RCSB], [http://www.ebi.ac.uk/pdbsum/1wqk PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/APT1_ANTEL APT1_ANTEL]] Potently and selectively blocks the HERG potassium voltage-gated channels KCNH2 (HERG1) KCNH6 (HERG2) and KCNH7 (HERG3). Acts by modifying the voltage dependence of the channel gating. Does not induce neurotoxic symptoms when injected into mice.<ref>PMID:12815161</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 09:16, 25 December 2014
Solution structure of APETx1, a specific peptide inhibitor of human Ether-a-go-go-related gene potassium channels from the venom of the sea anemone Anthopleura elegantissima: a new fold for an HERG toxin
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