2l4e
From Proteopedia
(Difference between revisions)
| Line 7: | Line 7: | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2l4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l4e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2l4e RCSB], [http://www.ebi.ac.uk/pdbsum/2l4e PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2l4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l4e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2l4e RCSB], [http://www.ebi.ac.uk/pdbsum/2l4e PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DCN1_YEAST DCN1_YEAST]] Required for neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. Does not act by preventing deneddylation, but rather facilitates neddylation, possibly by acting with HRT1/RBX1 to recruit the Nedd8-charged E2 UBC12 to the cullin component of SCF-type complexes.<ref>PMID:15988528</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 21:13, 25 December 2014
NMR structure of the UBA domain of S. cerevisiae Dcn1
| |||||||||||
