2lfh
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lfh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lfh RCSB], [http://www.ebi.ac.uk/pdbsum/2lfh PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lfh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lfh RCSB], [http://www.ebi.ac.uk/pdbsum/2lfh PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ID3_HUMAN ID3_HUMAN]] ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. Involved in myogenesis by inhibiting skeletal muscle and cardiac myocyte differentiation and promoting muscle precursor cells proliferation. Inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. May inhibit other transcription factors.<ref>PMID:8437843</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 18:42, 25 December 2014
Solution NMR Structure of the Helix-loop-Helix Domain of Human ID3 Protein, Northeast Structural Genomics Consortium Target HR3111A
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