1kwe
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kwe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1kwe RCSB], [http://www.ebi.ac.uk/pdbsum/1kwe PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kwe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1kwe RCSB], [http://www.ebi.ac.uk/pdbsum/1kwe PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GLYC_HRSVL GLYC_HRSVL]] Attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities (By similarity). Secreted glycoprotein G helps RSV escape antibody-dependent restriction of replication by acting as an antigen decoy and by modulating the activity of leukocytes bearing Fcgamma receptors (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 20:35, 24 December 2014
SOLUTION STRUCTURE OF THE CENTRAL CONSERVED REGION OF HUMAN RESPIRATORY SYNCYTIAL VIRUS ATTACHMENT GLYCOPROTEIN G
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Categories: Beck, A | Corvaia, N | Czaplicki, J | Ferrage, J | Haeuw, J F | Milon, A | Nguyen, T | Power, U F | Sugawara, M | Cysteine nose | Viral protein
