1tnd

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 4: Line 4:
|PDB= 1tnd |SIZE=350|CAPTION= <scene name='initialview01'>1tnd</scene>, resolution 2.2&Aring;
|PDB= 1tnd |SIZE=350|CAPTION= <scene name='initialview01'>1tnd</scene>, resolution 2.2&Aring;
|SITE=
|SITE=
-
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene> and <scene name='pdbligand=GSP:5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE'>GSP</scene>
+
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene> and <scene name='pdbligand=GSP:5&#39;-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE'>GSP</scene>
|ACTIVITY=
|ACTIVITY=
|GENE=
|GENE=
Line 30: Line 30:
[[Category: binding protein(gtp)]]
[[Category: binding protein(gtp)]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:20:43 2008''
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 23 13:45:45 2008''

Revision as of 11:45, 23 March 2008

Image:1tnd.gif


PDB ID 1tnd

Drag the structure with the mouse to rotate
, resolution 2.2Å
Ligands: , and
Coordinates: save as pdb, mmCIF, xml



THE 2.2 ANGSTROMS CRYSTAL STRUCTURE OF TRANSDUCIN-ALPHA COMPLEXED WITH GTP GAMMA S


Overview

The 2.2 A crystal structure of activated rod transducin, Gt alpha.GTP gamma S, shows the bound GTP gamma S molecule occluded deep in a cleft between a domain structurally homologous to small GTPases and a helical domain unique to heterotrimeric G proteins. The structure, when combined with biochemical and genetic studies, suggests: how an activated receptor might open this cleft to allow nucleotide exchange; a mechanism for GTP-induced changes in effector and receptor binding surfaces; and a mechanism for GTPase activity not evident from previous data.

About this Structure

1TND is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

The 2.2 A crystal structure of transducin-alpha complexed with GTP gamma S., Noel JP, Hamm HE, Sigler PB, Nature. 1993 Dec 16;366(6456):654-63. PMID:8259210

Page seeded by OCA on Sun Mar 23 13:45:45 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1tnd"
Personal tools