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1toa
From Proteopedia
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|PDB= 1toa |SIZE=350|CAPTION= <scene name='initialview01'>1toa</scene>, resolution 1.8Å | |PDB= 1toa |SIZE=350|CAPTION= <scene name='initialview01'>1toa</scene>, resolution 1.8Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand= | + | |LIGAND= <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1toa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1toa OCA], [http://www.ebi.ac.uk/pdbsum/1toa PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1toa RCSB]</span> | ||
}} | }} | ||
| Line 27: | Line 30: | ||
[[Category: Norgard, M V.]] | [[Category: Norgard, M V.]] | ||
[[Category: Radolf, J D.]] | [[Category: Radolf, J D.]] | ||
| - | [[Category: GOL]] | ||
| - | [[Category: ZN]] | ||
[[Category: abc transporter]] | [[Category: abc transporter]] | ||
[[Category: periplasmic binding protein]] | [[Category: periplasmic binding protein]] | ||
[[Category: zinc binding protein]] | [[Category: zinc binding protein]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:58:52 2008'' |
Revision as of 20:58, 30 March 2008
| |||||||
| , resolution 1.8Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
PERIPLASMIC ZINC BINDING PROTEIN TROA FROM TREPONEMA PALLIDUM
Overview
The crystal structure of recombinant TroA, a zinc-binding protein component of an ATP-binding cassette transport system in Treponema pallidum, was determined at a resolution of 1.8 A. The organization of the protein is largely similar to other periplasmic ligand-binding proteins (PLBP), in that two independent globular domains interact with each other to create a zinc-binding cleft between them. The structure has one bound zinc pentavalently coordinated to residues from both domains. Unlike previous PLBP structures that have an interdomain hinge composed of beta-strands, the N- and C-domains of TroA are linked by a single long backbone helix. This unique backbone helical conformation was possibly adopted to limit the hinge motion associated with ligand exchange.
About this Structure
1TOA is a Single protein structure of sequence from Treponema pallidum. Full crystallographic information is available from OCA.
Reference
Treponema pallidum TroA is a periplasmic zinc-binding protein with a helical backbone., Lee YH, Deka RK, Norgard MV, Radolf JD, Hasemann CA, Nat Struct Biol. 1999 Jul;6(7):628-33. PMID:10404217
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