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1u1s

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|ACTIVITY=
|ACTIVITY=
|GENE= hfq ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 Pseudomonas aeruginosa])
|GENE= hfq ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 Pseudomonas aeruginosa])
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|DOMAIN=
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|RELATEDENTRY=[[1hk9|1HK9]], [[1qk1|1QK1]], [[1qk2|1QK2]], [[1u1t|1U1T]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u1s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u1s OCA], [http://www.ebi.ac.uk/pdbsum/1u1s PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1u1s RCSB]</span>
}}
}}
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[[Category: structural genomic]]
[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:26:10 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:04:18 2008''

Revision as of 21:04, 30 March 2008

Image:1u1s.gif


PDB ID 1u1s

Drag the structure with the mouse to rotate
, resolution 1.60Å
Gene: hfq (Pseudomonas aeruginosa)
Related: 1HK9, 1QK1, 1QK2, 1U1T


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Hfq protein from Pseudomonas aeruginosa. Low-salt crystals


Overview

The structure of the Hfq protein from Pseudomonas aeruginosa was determined using two different ionic conditions. In both cases the molecules formed identical hexameric rings, but some variations in the crystal packing were revealed. Hfq belongs to the family of Sm/LSm proteins, the members of which can form hexameric as well as heptameric rings. Comparative analysis of known structures of this protein family shows that the fragment of the Sm-fold responsible for oligomerization is strongly structurally conserved. In the heptameric ring, three conserved hydrogen bonds between beta-strands of adjacent molecules hold together the monomers, whereas in the hexameric rings of Hfq an additional conserved inaccessible hydrogen bond between neighbouring monomers is observed.

About this Structure

1U1S is a Single protein structure of sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA.

Reference

Structure of Pseudomonas aeruginosa Hfq protein., Nikulin A, Stolboushkina E, Perederina A, Vassilieva I, Blaesi U, Moll I, Kachalova G, Yokoyama S, Vassylyev D, Garber M, Nikonov S, Acta Crystallogr D Biol Crystallogr. 2005 Feb;61(Pt 2):141-6. Epub 2005, Jan 19. PMID:15681864

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