1af9
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1af9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1af9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1af9 RCSB], [http://www.ebi.ac.uk/pdbsum/1af9 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1af9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1af9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1af9 RCSB], [http://www.ebi.ac.uk/pdbsum/1af9 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TETX_CLOTE TETX_CLOTE]] Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 14:32, 25 December 2014
TETANUS NEUROTOXIN C FRAGMENT
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