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1u9s
From Proteopedia
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|PDB= 1u9s |SIZE=350|CAPTION= <scene name='initialview01'>1u9s</scene>, resolution 2.90Å | |PDB= 1u9s |SIZE=350|CAPTION= <scene name='initialview01'>1u9s</scene>, resolution 2.90Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=BA:BARIUM ION'>BA</scene> | + | |LIGAND= <scene name='pdbligand=A:ADENOSINE-5'-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=BA:BARIUM+ION'>BA</scene>, <scene name='pdbligand=C:CYTIDINE-5'-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5'-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=U:URIDINE-5'-MONOPHOSPHATE'>U</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY=[[1nbs|1NBS]] | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u9s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u9s OCA], [http://www.ebi.ac.uk/pdbsum/1u9s PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1u9s RCSB]</span> | ||
}} | }} | ||
| Line 25: | Line 28: | ||
[[Category: Pan, T.]] | [[Category: Pan, T.]] | ||
[[Category: Xiao, Y.]] | [[Category: Xiao, Y.]] | ||
| - | [[Category: BA]] | ||
[[Category: p rna]] | [[Category: p rna]] | ||
[[Category: pre-trna]] | [[Category: pre-trna]] | ||
| Line 36: | Line 38: | ||
[[Category: trna]] | [[Category: trna]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:07:24 2008'' |
Revision as of 21:07, 30 March 2008
| |||||||
| , resolution 2.90Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , , , | ||||||
| Related: | 1NBS
| ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of the specificity domain of Ribonuclease P of the A-type
Overview
Large RNA molecules, such as ribozymes, fold with well-defined tertiary structures that are important for their activity. There are many instances of ribozymes with identical function but differences in their secondary structures, suggesting alternative tertiary folds. Here, we report a crystal structure of the 161-nucleotide specificity domain of an A-type ribonuclease P that differs in secondary and tertiary structure from the specificity domain of a B-type molecule. Despite the differences, the cores of the domains have similar three-dimensional structure. Remarkably, the similar geometry of the cores is stabilized by a different set of interactions involving distinct auxiliary elements.
About this Structure
1U9S is a Single protein structure of sequence from [1]. Full crystallographic information is available from OCA.
Reference
Basis for structural diversity in homologous RNAs., Krasilnikov AS, Xiao Y, Pan T, Mondragon A, Science. 2004 Oct 1;306(5693):104-7. PMID:15459389
Page seeded by OCA on Mon Mar 31 00:07:24 2008
