1dfq

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 8: Line 8:
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dfq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dfq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dfq RCSB], [http://www.ebi.ac.uk/pdbsum/1dfq PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dfq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dfq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dfq RCSB], [http://www.ebi.ac.uk/pdbsum/1dfq PDBsum]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[[http://www.uniprot.org/uniprot/TETX_CLOTE TETX_CLOTE]] Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 07:32, 25 December 2014

THE HC FRAGMENT OF TETANUS TOXIN COMPLEXED WITH SIALIC ACID

1dfq, resolution 2.60Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools