1dgp

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dgp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dgp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dgp RCSB], [http://www.ebi.ac.uk/pdbsum/1dgp PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dgp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dgp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dgp RCSB], [http://www.ebi.ac.uk/pdbsum/1dgp PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ARIS_PENRO ARIS_PENRO]] Catalyzes the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic sesquiterpene aristolochene. Produces germacrene A as an enzyme-bound intermediate that is not released by the enzyme, but is further cyclized to produce aristolochene. Aristolochene is the likely parent compound for a number of sesquiterpenoid toxins produced by filamentous fungi.<ref>PMID:8440737</ref> <ref>PMID:15186158</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 11:58, 25 December 2014

ARISTOLOCHENE SYNTHASE FARNESOL COMPLEX

1dgp, resolution 2.80Å

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